let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration

Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor cells with stem cell characteristics. This necessity for retina regeneration is often compromised in mammals. We explored the significance of developmentally inevitable Sonic hedgehog signaling and found its ne...

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發表在:Cell Rep
Main Authors: Kaur, Simran, Gupta, Shivangi, Chaudhary, Mansi, Khursheed, Mohammad Anwar, Mitra, Soumitra, Kurup, Akshai Janardhana, Ramachandran, Rajesh
格式: Artigo
語言:Inglês
出版: Cell Press 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946716/
https://ncbi.nlm.nih.gov/pubmed/29719254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.002
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