let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration

Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor cells with stem cell characteristics. This necessity for retina regeneration is often compromised in mammals. We explored the significance of developmentally inevitable Sonic hedgehog signaling and found its ne...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Kaur, Simran, Gupta, Shivangi, Chaudhary, Mansi, Khursheed, Mohammad Anwar, Mitra, Soumitra, Kurup, Akshai Janardhana, Ramachandran, Rajesh
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946716/
https://ncbi.nlm.nih.gov/pubmed/29719254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.002
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