let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration

Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor cells with stem cell characteristics. This necessity for retina regeneration is often compromised in mammals. We explored the significance of developmentally inevitable Sonic hedgehog signaling and found its ne...

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Publicado en:Cell Rep
Autores principales: Kaur, Simran, Gupta, Shivangi, Chaudhary, Mansi, Khursheed, Mohammad Anwar, Mitra, Soumitra, Kurup, Akshai Janardhana, Ramachandran, Rajesh
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946716/
https://ncbi.nlm.nih.gov/pubmed/29719254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.002
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