Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish

Tgf-β signaling is a major antiproliferative pathway governing different biological functions, including cellular reprogramming. Upon injury, Müller glial cells of zebrafish retina reprogram to form progenitors (MGPCs) essential for regeneration. Here, the significance of Tgf-β signaling for inducin...

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Gepubliceerd in:iScience
Hoofdauteurs: Sharma, Poonam, Gupta, Shivangi, Chaudhary, Mansi, Mitra, Soumitra, Chawla, Bindia, Khursheed, Mohammad Anwar, Saran, Navnoor Kaur, Ramachandran, Rajesh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994856/
https://ncbi.nlm.nih.gov/pubmed/32004993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.100817
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