Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling

Neural stem/progenitor cells (NSPCs) originating from the subventricular zone (SVZ) contribute to brain repair during CNS disease. The microenvironment within the SVZ stem cell niche controls NSPC fate. However, extracellular factors within the niche that trigger astrogliogenesis over neurogenesis d...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Pous, Lauriane, Deshpande, Sachin S., Nath, Suvra, Mezey, Szilvia, Malik, Subash C., Schildge, Sebastian, Bohrer, Christian, Topp, Könül, Pfeifer, Dietmar, Fernández-Klett, Francisco, Doostkam, Soroush, Galanakis, Dennis K., Taylor, Verdon, Akassoglou, Katerina, Schachtrup, Christian
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994610/
https://ncbi.nlm.nih.gov/pubmed/32005867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14466-y
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