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Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling

Neural stem/progenitor cells (NSPCs) originating from the subventricular zone (SVZ) contribute to brain repair during CNS disease. The microenvironment within the SVZ stem cell niche controls NSPC fate. However, extracellular factors within the niche that trigger astrogliogenesis over neurogenesis d...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Pous, Lauriane, Deshpande, Sachin S., Nath, Suvra, Mezey, Szilvia, Malik, Subash C., Schildge, Sebastian, Bohrer, Christian, Topp, Könül, Pfeifer, Dietmar, Fernández-Klett, Francisco, Doostkam, Soroush, Galanakis, Dennis K., Taylor, Verdon, Akassoglou, Katerina, Schachtrup, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994610/
https://ncbi.nlm.nih.gov/pubmed/32005867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14466-y
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