تحميل...
The iron chelator Deferasirox causes severe mitochondrial swelling without depolarization due to a specific effect on inner membrane permeability
The iron chelator Deferasirox (DFX) causes severe toxicity in patients for reasons that were previously unexplained. Here, using the kidney as a clinically relevant in vivo model for toxicity together with a broad range of experimental techniques, including live cell imaging and in vitro biophysical...
محفوظ في:
| الحاوية / القاعدة: | Sci Rep |
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| المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Nature Publishing Group UK
2020
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6994599/ https://ncbi.nlm.nih.gov/pubmed/32005861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58386-9 |
| الوسوم: |
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