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Structure of transcription coactivator SAGA

Gene transcription by RNA polymerase II is regulated by activator proteins that recruit the coactivator complexes SAGA(1,2) and TFIID(2–4). SAGA is globally required for regulated transcription(5) and conserved amongst eukaryotes(6). SAGA contains four modules(7–9), the activator-binding Tra1 module...

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Bibliographic Details
Published in:Nature
Main Authors: Wang, Haibo, Dienemann, Christian, Stützer, Alexandra, Urlaub, Henning, Cheung, Alan C.M., Cramer, Patrick
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994259/
https://ncbi.nlm.nih.gov/pubmed/31969703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-1933-5
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