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Structure of transcription coactivator SAGA

Gene transcription by RNA polymerase II is regulated by activator proteins that recruit the coactivator complexes SAGA(1,2) and TFIID(2–4). SAGA is globally required for regulated transcription(5) and conserved amongst eukaryotes(6). SAGA contains four modules(7–9), the activator-binding Tra1 module...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Wang, Haibo, Dienemann, Christian, Stützer, Alexandra, Urlaub, Henning, Cheung, Alan C.M., Cramer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994259/
https://ncbi.nlm.nih.gov/pubmed/31969703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-1933-5
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