TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination

Increased rates of locoregional recurrence are observed in patients with basal-like breast cancer (BC) despite the use of radiation therapy (RT); therefore, approaches that result in radiosensitization of basal-like BC are critically needed. Using patients’ tumor gene expression data from 4 independ...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Chandler, Benjamin C., Moubadder, Leah, Ritter, Cassandra L., Liu, Meilan, Cameron, Meleah, Wilder-Romans, Kari, Zhang, Amanda, Pesch, Andrea M., Michmerhuizen, Anna R., Hirsh, Nicole, Androsiglio, Marlie, Ward, Tanner, Olsen, Eric, Niknafs, Yashar S., Merajver, Sofia, Thomas, Dafydd G., Brown, Powel H., Lawrence, Theodore S., Nyati, Shyam, Pierce, Lori J., Chinnaiyan, Arul, Speers, Corey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994133/
https://ncbi.nlm.nih.gov/pubmed/31961339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130435
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