TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination

Increased rates of locoregional recurrence are observed in patients with basal-like breast cancer (BC) despite the use of radiation therapy (RT); therefore, approaches that result in radiosensitization of basal-like BC are critically needed. Using patients’ tumor gene expression data from 4 independ...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Chandler, Benjamin C., Moubadder, Leah, Ritter, Cassandra L., Liu, Meilan, Cameron, Meleah, Wilder-Romans, Kari, Zhang, Amanda, Pesch, Andrea M., Michmerhuizen, Anna R., Hirsh, Nicole, Androsiglio, Marlie, Ward, Tanner, Olsen, Eric, Niknafs, Yashar S., Merajver, Sofia, Thomas, Dafydd G., Brown, Powel H., Lawrence, Theodore S., Nyati, Shyam, Pierce, Lori J., Chinnaiyan, Arul, Speers, Corey
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994133/
https://ncbi.nlm.nih.gov/pubmed/31961339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130435
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