Toll-like Receptor 8 Stability Is Regulated by Ring Finger 216 in Response to Circulating MicroRNAs

TLR8 (Toll-like receptor 8) is an intracellular pattern recognition receptor that senses RNA in endosomes to initiate innate immune signaling through NF-κB, and mechanisms regulating TLR8 protein abundance are not completely understood. Protein degradation is a cellular process controlling protein c...

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Bibliografiske detaljer
Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Evankovich, John, Lear, Travis, Baldwin, Courtney, Chen, Yanwen, White, Virginia, Villandre, John, Londino, James, Liu, Yuan, McVerry, Bryan, Kitsios, Georgios D., Mallampalli, Rama K., Chen, Bill B.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993540/
https://ncbi.nlm.nih.gov/pubmed/31385713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0373OC
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