Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway

BACKGROUND: Aspirin, as a non-steroidal anti-inflammatory drug, can improve the survival rate of patients with colorectal cancer, while aspirin is effective in patients with PIK3CA mutant colorectal cancer (CRC). However, the mechanism of aspirin in the treatment of PIK3CA mutated CRC patients remai...

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Udgivet i:Mol Med
Main Authors: Chen, Zhihang, Wang, Chun, Dong, Hao, Wang, Xing, Gao, Feng, Zhang, Sen, Zhang, Xiaolong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993447/
https://ncbi.nlm.nih.gov/pubmed/32000660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-020-0139-5
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