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Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway

BACKGROUND: Aspirin, as a non-steroidal anti-inflammatory drug, can improve the survival rate of patients with colorectal cancer, while aspirin is effective in patients with PIK3CA mutant colorectal cancer (CRC). However, the mechanism of aspirin in the treatment of PIK3CA mutated CRC patients remai...

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Podrobná bibliografie
Vydáno v:Mol Med
Hlavní autoři: Chen, Zhihang, Wang, Chun, Dong, Hao, Wang, Xing, Gao, Feng, Zhang, Sen, Zhang, Xiaolong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993447/
https://ncbi.nlm.nih.gov/pubmed/32000660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-020-0139-5
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