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Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway

BACKGROUND: Aspirin, as a non-steroidal anti-inflammatory drug, can improve the survival rate of patients with colorectal cancer, while aspirin is effective in patients with PIK3CA mutant colorectal cancer (CRC). However, the mechanism of aspirin in the treatment of PIK3CA mutated CRC patients remai...

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Bibliografski detalji
Izdano u:Mol Med
Glavni autori: Chen, Zhihang, Wang, Chun, Dong, Hao, Wang, Xing, Gao, Feng, Zhang, Sen, Zhang, Xiaolong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993447/
https://ncbi.nlm.nih.gov/pubmed/32000660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-020-0139-5
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