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Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway

BACKGROUND: Aspirin, as a non-steroidal anti-inflammatory drug, can improve the survival rate of patients with colorectal cancer, while aspirin is effective in patients with PIK3CA mutant colorectal cancer (CRC). However, the mechanism of aspirin in the treatment of PIK3CA mutated CRC patients remai...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Chen, Zhihang, Wang, Chun, Dong, Hao, Wang, Xing, Gao, Feng, Zhang, Sen, Zhang, Xiaolong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993447/
https://ncbi.nlm.nih.gov/pubmed/32000660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-020-0139-5
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