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Identification and characterization of two conserved G-quadruplex forming motifs in the Nipah virus genome and their interaction with G-quadruplex specific ligands

The G-quadruplex (GQ) motifs are considered as potential drug-target sites for several human pathogenic viruses such as Zika, Hepatitis, Ebola, and Human Herpesviruses. The recent outbreaks of Nipah virus (NiV) in India, the highly fatal emerging zoonotic virus is a potential threat to global health...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Majee, Prativa, Kumar Mishra, Subodh, Pandya, Nirali, Shankar, Uma, Pasadi, Sanjeev, Muniyappa, K., Nayak, Debasis, Kumar, Amit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992748/
https://ncbi.nlm.nih.gov/pubmed/32001794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58406-8
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