Conserved G-Quadruplex Motifs in Gene Promoter Region Reveals a Novel Therapeutic Approach to Target Multi-Drug Resistance Klebsiella pneumoniae

An opportunistic pathogen, Klebsiella pneumoniae is known to cause life-threating nosocomial infection with a high rate of morbidity and mortality. Evolutions of multi-drug-resistant and hyper-virulent strains of K. pneumoniae make the situation worse. Currently, there is no incisive drug molecule a...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Autores principales: Shankar, Uma, Jain, Neha, Mishra, Subodh Kumar, Sharma, Tarun Kumar, Kumar, Amit
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344255/
https://ncbi.nlm.nih.gov/pubmed/32714288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01269
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