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Identification and characterization of two conserved G-quadruplex forming motifs in the Nipah virus genome and their interaction with G-quadruplex specific ligands

The G-quadruplex (GQ) motifs are considered as potential drug-target sites for several human pathogenic viruses such as Zika, Hepatitis, Ebola, and Human Herpesviruses. The recent outbreaks of Nipah virus (NiV) in India, the highly fatal emerging zoonotic virus is a potential threat to global health...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Majee, Prativa, Kumar Mishra, Subodh, Pandya, Nirali, Shankar, Uma, Pasadi, Sanjeev, Muniyappa, K., Nayak, Debasis, Kumar, Amit
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992748/
https://ncbi.nlm.nih.gov/pubmed/32001794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58406-8
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