Two faces of bivalent domain regulate VEGFA responsiveness and angiogenesis

The bivalent domain (BD) at promoter region is an unique epigenetic feature poised for activation or repression during cell differentiation in embryonic stem cell. However, the function of BDs in already differentiated cells remains exclusive. By profiling the epigenetic landscape of endothelial cel...

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Udgivet i:Cell Death Dis
Main Authors: Chen, Jiahuan, Liang, Xiaodong, Zhang, Shasha, Wang, Shiyan, Garcia, Sara P., Yan, Pengyi, Yu, Huijing, Li, Zixuan, Liu, Li, Zhang, Fang, Wei, Weiting, Le, Huangying, Zhang, Yan, Yuan, Guo-cheng, Chen, Sun, Chen, Yingwei, Sun, Kun, Pu, William T., Zhang, Bing
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992747/
https://ncbi.nlm.nih.gov/pubmed/32001672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2228-3
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