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Analysis of the polycystin complex (PCC) in human urinary exosome–like vesicles (ELVs)

The polycystin–1 (PC1), polycystin–2 (PC2) and fibrocystin proteins, the respective products of the PKD1, PKD2 and PKHD1 genes, are abundant in urinary exosome–like vesicles (ELVs) where they form the polycystin complex (PCC). ELVs are 100 nm diameter membrane vesicles shed into the urine by the cel...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Lea, Wendy A., McGreal, Kerri, Sharma, Madhulika, Parnell, Stephen C., Zelenchuk, Lesya, Charlesworth, M. Cristine, Madden, Benjamin J., Johnson, Kenneth L., McCormick, Daniel J., Hogan, Marie C., Ward, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992733/
https://ncbi.nlm.nih.gov/pubmed/32001768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58087-3
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