Characterization of PKD Protein-Positive Exosome-Like Vesicles

Proteins associated with autosomal dominant and autosomal recessive polycystic kidney disease (polycystin-1, polycystin-2, and fibrocystin) localize to various subcellular compartments, but their functional site is thought to be on primary cilia. PC1+ vesicles surround cilia in Pkhd1(del2/del2) mice...

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Hauptverfasser: Hogan, Marie C., Manganelli, Luca, Woollard, John R., Masyuk, Anatoliy I., Masyuk, Tatyana V., Tammachote, Rachaneekorn, Huang, Bing Q., Leontovich, Alexey A., Beito, Thomas G., Madden, Benjamin J., Charlesworth, M. Cristine, Torres, Vicente E., LaRusso, Nicholas F., Harris, Peter C., Ward, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2009
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637052/
https://ncbi.nlm.nih.gov/pubmed/19158352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008060564
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