Characterization of PKD Protein-Positive Exosome-Like Vesicles

Proteins associated with autosomal dominant and autosomal recessive polycystic kidney disease (polycystin-1, polycystin-2, and fibrocystin) localize to various subcellular compartments, but their functional site is thought to be on primary cilia. PC1+ vesicles surround cilia in Pkhd1(del2/del2) mice...

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Auteurs principaux: Hogan, Marie C., Manganelli, Luca, Woollard, John R., Masyuk, Anatoliy I., Masyuk, Tatyana V., Tammachote, Rachaneekorn, Huang, Bing Q., Leontovich, Alexey A., Beito, Thomas G., Madden, Benjamin J., Charlesworth, M. Cristine, Torres, Vicente E., LaRusso, Nicholas F., Harris, Peter C., Ward, Christopher J.
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2009
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637052/
https://ncbi.nlm.nih.gov/pubmed/19158352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008060564
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