Identification of Biomarkers for PKD1 Using Urinary Exosomes

Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of ESRD. Affected individuals inherit a defective copy of either PKD1 or PKD2, which encode polycystin-1 (PC1) or polycystin-2 (PC2), respectively. PC1 and PC2 are secreted on urinary exosome-like vesicles (ELVs) (100-nm diameter...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Hogan, Marie C., Bakeberg, Jason L., Gainullin, Vladimir G., Irazabal, Maria V., Harmon, Amber J., Lieske, John C., Charlesworth, M. Cristine, Johnson, Kenneth L., Madden, Benjamin J., Zenka, Roman M., McCormick, Daniel J., Sundsbak, Jamie L., Heyer, Christina M., Torres, Vicente E., Harris, Peter C., Ward, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483583/
https://ncbi.nlm.nih.gov/pubmed/25475747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014040354
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