Subfractionation, characterization and in-depth proteomic analysis of glomerular membrane vesicles in human urine

Urinary exosome-like vesicles (ELVs) are a heterogenous mixture (diameter 40–200nm) containing vesicles shed from all segments of the nephron including glomerular podocytes. Contamination with Tamm Horsfall protein (THP) oligomers has hampered their isolation and proteomic analysis. Here we improved...

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Bibliographische Detailangaben
Hauptverfasser: Hogan, Marie C., Johnson, Kenneth L., Zenka, Roman M., Charlesworth, M. Cristine, Madden, Benjamin J., Mahoney, Doug W., Oberg, Ann L., Huang, Bing Q., Nesbitt, Lisa L., Bakeberg, Jason L., Bergen, H. Robert, Ward, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008663/
https://ncbi.nlm.nih.gov/pubmed/24196483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.422
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