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Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management

Opioid drugs are the gold standard for the management of pain, but their use is severely limited by dangerous and unpleasant side effects. All clinically available opioid analgesics bind to and activate the mu-opioid receptor (MOR), a heterotrimeric G-protein-coupled receptor, to produce analgesia....

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Senese, Nicolas B., Kandasamy, Ram, Kochan, Kelsey E., Traynor, John R.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992652/
https://ncbi.nlm.nih.gov/pubmed/32038168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00005
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