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Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management

Opioid drugs are the gold standard for the management of pain, but their use is severely limited by dangerous and unpleasant side effects. All clinically available opioid analgesics bind to and activate the mu-opioid receptor (MOR), a heterotrimeric G-protein-coupled receptor, to produce analgesia....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Mol Neurosci
Egile Nagusiak: Senese, Nicolas B., Kandasamy, Ram, Kochan, Kelsey E., Traynor, John R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992652/
https://ncbi.nlm.nih.gov/pubmed/32038168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00005
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