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μ-Opioid Receptors and Regulators of G protein Signaling (RGS) proteins: From a symposium on new concepts in mu-opioid pharmacology
Mu-opioid receptors (MOR) are the therapeutic target for opiate analgesic drugs and also mediate many of the side-effects and addiction liability of these compounds. MOR is a seven-transmembrane domain receptor that couples to intracellular signaling molecules by activating heterotrimeric G proteins...
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
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2011
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Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288798/ https://ncbi.nlm.nih.gov/pubmed/22129844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2011.10.027 |
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