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Mu opioid receptor activation enhances regulator of G protein signaling 4 association with the mu opioid receptor/G protein complex in a GTP‐dependent manner

The interaction of Regulator of G protein Signaling 4 (RGS4) with the rat mu opioid receptor (MOR)/G protein complex was investigated. Solubilized MOR from rat brain membranes was immunoprecipitated in the presence of RGS4 with antibodies against the N‐terminus of MOR (anti‐MOR(10–70)). Activation o...

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Détails bibliographiques
Publié dans:J Neurochem
Auteurs principaux: Santhappan, Rema, Crowder, Alicia Tamara, Gouty, Shawn, Cox, Brian M., Côté, Thomas E.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034817/
https://ncbi.nlm.nih.gov/pubmed/26119705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13222
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