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PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer

PIM kinases have been shown to play a role in prostate cancer development and progression, as well as in some of the hallmarks of cancer, especially proliferation and apoptosis. Their upregulation in prostate cancer has been correlated with decreased patient overall survival and therapy resistance....

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Luszczak, Sabina, Kumar, Christopher, Sathyadevan, Vignesh Krishna, Simpson, Benjamin S., Gately, Kathy A., Whitaker, Hayley C., Heavey, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992635/
https://ncbi.nlm.nih.gov/pubmed/32296034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0109-y
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