PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer

PIM kinases have been shown to play a role in prostate cancer development and progression, as well as in some of the hallmarks of cancer, especially proliferation and apoptosis. Their upregulation in prostate cancer has been correlated with decreased patient overall survival and therapy resistance....

Full description

Saved in:
Bibliographic Details
Published in:Signal Transduct Target Ther
Main Authors: Luszczak, Sabina, Kumar, Christopher, Sathyadevan, Vignesh Krishna, Simpson, Benjamin S., Gately, Kathy A., Whitaker, Hayley C., Heavey, Susan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992635/
https://ncbi.nlm.nih.gov/pubmed/32296034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0109-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items