Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans

BACKGROUND: HIV vaccine trials routinely measure multiple vaccine-elicited immune responses to compare regimens and study their potential associations with protection. Here we employ unsupervised learning tools facilitated by a bidirectional power transformation to explore the multivariate binding a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhao, Lue Ping, Fiore-Gartland, Andrew, Carpp, Lindsay N., Cohen, Kristen W., Rouphael, Nadine, Fleurs, Llewellyn, Dintwe, One, Zhao, Michael, Moodie, Zoe, Fong, Youyi, Garrett, Nigel, Huang, Ying, Innes, Craig, Janes, Holly E., Lazarus, Erica, Michael, Nelson L., Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Robb, Merlin L., De Rosa, Stephen C., Corey, Lawrence, Gray, Glenda E., Seaton, Kelly E., Yates, Nicole L., McElrath, M. Juliana, Frahm, Nicole, Tomaras, Georgia D., Gilbert, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992005/
https://ncbi.nlm.nih.gov/pubmed/31999736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226803
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