Understanding mechanistic relationships between IgG titers and Fc effector functions: a computational framework to assess polyfunctionality

IntroductionRecent vaccine and infectious disease studies have highlighted the importance of antibodies that activate cellular Fc functions, including antibody-dependent cellular phagocytosis (ADCP) and antibody-dependent cellular cytotoxicity (ADCC), which are mediated by different Fc gamma Recepto...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Suzanne K. Shoffner-Beck, Robert M. Theisen, Kade E. Wong, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Stephen Kent, Amy W. Chung, Kelly B. Arnold
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-09-01
Colecção:Frontiers in Immunology
Assuntos:
antibody-mediated effector functions
antibody-dependent cellular cytotoxicity (ADCC)
human immunodeficiency virus (HIV)
ordinary differential equation model
mechanistic model
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578500/full
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados