Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans

BACKGROUND: HIV vaccine trials routinely measure multiple vaccine-elicited immune responses to compare regimens and study their potential associations with protection. Here we employ unsupervised learning tools facilitated by a bidirectional power transformation to explore the multivariate binding a...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Zhao, Lue Ping, Fiore-Gartland, Andrew, Carpp, Lindsay N., Cohen, Kristen W., Rouphael, Nadine, Fleurs, Llewellyn, Dintwe, One, Zhao, Michael, Moodie, Zoe, Fong, Youyi, Garrett, Nigel, Huang, Ying, Innes, Craig, Janes, Holly E., Lazarus, Erica, Michael, Nelson L., Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Robb, Merlin L., De Rosa, Stephen C., Corey, Lawrence, Gray, Glenda E., Seaton, Kelly E., Yates, Nicole L., McElrath, M. Juliana, Frahm, Nicole, Tomaras, Georgia D., Gilbert, Peter B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992005/
https://ncbi.nlm.nih.gov/pubmed/31999736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226803
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