Up‐regulation of HDACs, a harbinger of uraemic endothelial dysfunction, is prevented by defibrotide

Endothelial dysfunction is an earlier contributor to the development of atherosclerosis in chronic kidney disease (CKD), in which the role of epigenetic triggers cannot be ruled out. Endothelial protective strategies, such as defibrotide (DF), may be useful in this scenario. We evaluated changes ind...

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Pubblicato in:J Cell Mol Med
Autori principali: Palomo, Marta, Vera, Manel, Martin, Susana, Torramadé‐Moix, Sergi, Martinez‐Sanchez, Julia, Belen Moreno, Ana, Carreras, Enric, Escolar, Ginés, Cases, Aleix, Díaz‐Ricart, Maribel
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991634/
https://ncbi.nlm.nih.gov/pubmed/31782253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14865
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