Acute Graft-vs.-Host Disease-Associated Endothelial Activation in vitro Is Prevented by Defibrotide

Angiogenesis and endothelial activation and dysfunction have been associated with acute graft-vs.-host disease (aGVHD), pointing to the endothelium as a potential target for pharmacological intervention. Defibrotide (DF) is a drug with an endothelium-protective effect that has been approved for the...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Martinez-Sanchez, Julia, Hamelmann, Hannah, Palomo, Marta, Mir, Enrique, Moreno-Castaño, Ana Belen, Torramade, Sergi, Rovira, Montserrat, Escolar, Ginés, Cordes, Steffen, Kalupa, Martina, Mertlitz, Sarah, Riesner, Katarina, Carreras, Enric, Penack, Olaf, Diaz-Ricart, Maribel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794443/
https://ncbi.nlm.nih.gov/pubmed/31649666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02339
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