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Up‐regulation of HDACs, a harbinger of uraemic endothelial dysfunction, is prevented by defibrotide

Endothelial dysfunction is an earlier contributor to the development of atherosclerosis in chronic kidney disease (CKD), in which the role of epigenetic triggers cannot be ruled out. Endothelial protective strategies, such as defibrotide (DF), may be useful in this scenario. We evaluated changes ind...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Palomo, Marta, Vera, Manel, Martin, Susana, Torramadé‐Moix, Sergi, Martinez‐Sanchez, Julia, Belen Moreno, Ana, Carreras, Enric, Escolar, Ginés, Cases, Aleix, Díaz‐Ricart, Maribel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991634/
https://ncbi.nlm.nih.gov/pubmed/31782253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14865
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