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Gene-gene interaction: the curse of dimensionality
Identified genetic variants from genome wide association studies frequently show only modest effects on the disease risk, leading to the “missing heritability” problem. An avenue, to account for a part of this “missingness” is to evaluate gene-gene interactions (epistasis) thereby elucidating their...
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| Publicado no: | Ann Transl Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AME Publishing Company
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6989881/ https://ncbi.nlm.nih.gov/pubmed/32042829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.12.87 |
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