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Gene-gene interaction: the curse of dimensionality
Identified genetic variants from genome wide association studies frequently show only modest effects on the disease risk, leading to the “missing heritability” problem. An avenue, to account for a part of this “missingness” is to evaluate gene-gene interactions (epistasis) thereby elucidating their...
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| Publié dans: | Ann Transl Med |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
AME Publishing Company
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6989881/ https://ncbi.nlm.nih.gov/pubmed/32042829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.12.87 |
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