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Gene-gene interaction: the curse of dimensionality

Identified genetic variants from genome wide association studies frequently show only modest effects on the disease risk, leading to the “missing heritability” problem. An avenue, to account for a part of this “missingness” is to evaluate gene-gene interactions (epistasis) thereby elucidating their...

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Bibliografski detalji
Izdano u:Ann Transl Med
Glavni autori: Chattopadhyay, Amrita, Lu, Tzu-Pin
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989881/
https://ncbi.nlm.nih.gov/pubmed/32042829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.12.87
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