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Allelic H3K27me3 to allelic DNA methylation switch maintains noncanonical imprinting in extraembryonic cells

Faithful maintenance of genomic imprinting is essential for mammalian development. While germline DNA methylation–dependent (canonical) imprinting is relatively stable during development, the recently found oocyte-derived H3K27me3-mediated noncanonical imprinting is mostly transient in early embryos...

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Bibliografiska uppgifter
I publikationen:Sci Adv
Huvudupphovsmän: Chen, Zhiyuan, Yin, Qiangzong, Inoue, Azusa, Zhang, Chunxia, Zhang, Yi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Association for the Advancement of Science 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989337/
https://ncbi.nlm.nih.gov/pubmed/32064321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay7246
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