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Pharmacodynamic principles and the time course of delayed and cumulative drug effects

This tutorial reviews the principles of the concentration — effect relationship for the usual case when drug effects are delayed relative to changes in circulating concentrations. The key processes determining delay are distribution from the circulation to the receptor, binding to the receptor to pr...

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Detalhes bibliográficos
Publicado no:Transl Clin Pharmacol
Autor principal: Holford, Nick
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Clinical Pharmacology and Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989261/
https://ncbi.nlm.nih.gov/pubmed/32055549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2018.26.2.56
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