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Pharmacodynamic principles and the time course of delayed and cumulative drug effects

This tutorial reviews the principles of the concentration — effect relationship for the usual case when drug effects are delayed relative to changes in circulating concentrations. The key processes determining delay are distribution from the circulation to the receptor, binding to the receptor to pr...

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Vydáno v:Transl Clin Pharmacol
Hlavní autor: Holford, Nick
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Clinical Pharmacology and Therapeutics 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989261/
https://ncbi.nlm.nih.gov/pubmed/32055549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2018.26.2.56
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