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Pharmacodynamic principles and target concentration intervention

This tutorial reviews the principles of dose individualisation with an emphasis on target concentration intervention (TCI). Once a target effect is chosen then pharmacodynamics can predict the target concentration and pharmacokinetics can predict the target dose to achieve the required response. Dos...

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Publicat a:Transl Clin Pharmacol
Autor principal: Holford, Nick
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Clinical Pharmacology and Therapeutics 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989251/
https://ncbi.nlm.nih.gov/pubmed/32055568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2018.26.4.150
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