Optimizing Mycophenolic Acid Exposure in Kidney Transplant Recipients: Time for Target Concentration Intervention

The immunosuppressive agent mycophenolate is used extensively in kidney transplantation, yet dosing strategy applied varies markedly from fixed dosing (“one-dose-fits-all”), to mycophenolic acid (MPA) trough concentration monitoring, to dose optimization to an MPA exposure target (as area under the...

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Veröffentlicht in:Transplantation
Hauptverfasser: Metz, David K., Holford, Nick, Kausman, Joshua Y., Walker, Amanda, Cranswick, Noel, Staatz, Christine E., Barraclough, Katherine A., Ierino, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756255/
https://ncbi.nlm.nih.gov/pubmed/31584924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002762
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