Case report: recurrent pituitary adenoma has increased load of somatic variants

BACKGROUND: Pituitary adenomas (PA) have an increased potential for relapse in one to 5 years after resection. In this study, we investigated the genetic differences in genomic DNA of primary and rapidly recurrent tumours in the same patient to explain the causality mechanisms of PA recurrence. CASE...

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Dettagli Bibliografici
Pubblicato in:BMC Endocr Disord
Autori principali: Peculis, Raitis, Balcere, Inga, Radovica-Spalvina, Ilze, Konrade, Ilze, Caune, Olivija, Megnis, Kaspars, Rovite, Vita, Stukens, Janis, Nazarovs, Jurijs, Breiksa, Austra, Kiecis, Aigars, Silamikelis, Ivars, Pirags, Valdis, Klovins, Janis
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Case Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988340/
https://ncbi.nlm.nih.gov/pubmed/31996211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12902-020-0493-x
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