Case report: recurrent pituitary adenoma has increased load of somatic variants

BACKGROUND: Pituitary adenomas (PA) have an increased potential for relapse in one to 5 years after resection. In this study, we investigated the genetic differences in genomic DNA of primary and rapidly recurrent tumours in the same patient to explain the causality mechanisms of PA recurrence. CASE...

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Détails bibliographiques
Publié dans:BMC Endocr Disord
Auteurs principaux: Peculis, Raitis, Balcere, Inga, Radovica-Spalvina, Ilze, Konrade, Ilze, Caune, Olivija, Megnis, Kaspars, Rovite, Vita, Stukens, Janis, Nazarovs, Jurijs, Breiksa, Austra, Kiecis, Aigars, Silamikelis, Ivars, Pirags, Valdis, Klovins, Janis
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Case Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988340/
https://ncbi.nlm.nih.gov/pubmed/31996211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12902-020-0493-x
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