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Case report: recurrent pituitary adenoma has increased load of somatic variants

BACKGROUND: Pituitary adenomas (PA) have an increased potential for relapse in one to 5 years after resection. In this study, we investigated the genetic differences in genomic DNA of primary and rapidly recurrent tumours in the same patient to explain the causality mechanisms of PA recurrence. CASE...

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Bibliografische gegevens
Gepubliceerd in:BMC Endocr Disord
Hoofdauteurs: Peculis, Raitis, Balcere, Inga, Radovica-Spalvina, Ilze, Konrade, Ilze, Caune, Olivija, Megnis, Kaspars, Rovite, Vita, Stukens, Janis, Nazarovs, Jurijs, Breiksa, Austra, Kiecis, Aigars, Silamikelis, Ivars, Pirags, Valdis, Klovins, Janis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988340/
https://ncbi.nlm.nih.gov/pubmed/31996211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12902-020-0493-x
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