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Synthesis of [3,3-(2)H(2)]-Dihydroartemisinic Acid to Measure the Rate of Nonenzymatic Conversion of Dihydroartemisinic Acid to Artemisinin
[Image: see text] Dihydroartemisinic acid is the biosynthetic precursor to artemisinin, the endoperoxide-containing natural product used to treat malaria. The conversion of dihydroartemisinic acid to artemisinin is a cascade reaction that involves C–C bond cleavage, hydroperoxide incorporation, and...
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| Publicado no: | J Nat Prod |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society and American
Society of Pharmacognosy
2019
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6988128/ https://ncbi.nlm.nih.gov/pubmed/31859509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.9b00686 |
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