Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

Hydrogen sulfide (H(2)S) is involved in numerous pathophysiological processes and shares overlapping functions with CO and •NO. However, the importance of host-derived H(2)S in microbial pathogenesis is unknown. Here we show that Mtb-infected mice deficient in the H(2)S-producing enzyme cystathionin...

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Pubblicato in:Nat Commun
Autori principali: Saini, Vikram, Chinta, Krishna C., Reddy, Vineel P., Glasgow, Joel N., Stein, Asaf, Lamprecht, Dirk A., Rahman, Md. Aejazur, Mackenzie, Jared S., Truebody, Barry E., Adamson, John H., Kunota, Tafara T. R., Bailey, Shannon M., Moellering, Douglas R., Lancaster, Jack R., Steyn, Adrie J. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987094/
https://ncbi.nlm.nih.gov/pubmed/31992699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14132-y
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