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Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

Hydrogen sulfide (H(2)S) is involved in numerous pathophysiological processes and shares overlapping functions with CO and •NO. However, the importance of host-derived H(2)S in microbial pathogenesis is unknown. Here we show that Mtb-infected mice deficient in the H(2)S-producing enzyme cystathionin...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Saini, Vikram, Chinta, Krishna C., Reddy, Vineel P., Glasgow, Joel N., Stein, Asaf, Lamprecht, Dirk A., Rahman, Md. Aejazur, Mackenzie, Jared S., Truebody, Barry E., Adamson, John H., Kunota, Tafara T. R., Bailey, Shannon M., Moellering, Douglas R., Lancaster, Jack R., Steyn, Adrie J. C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987094/
https://ncbi.nlm.nih.gov/pubmed/31992699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14132-y
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