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Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

Hydrogen sulfide (H(2)S) is involved in numerous pathophysiological processes and shares overlapping functions with CO and •NO. However, the importance of host-derived H(2)S in microbial pathogenesis is unknown. Here we show that Mtb-infected mice deficient in the H(2)S-producing enzyme cystathionin...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Saini, Vikram, Chinta, Krishna C., Reddy, Vineel P., Glasgow, Joel N., Stein, Asaf, Lamprecht, Dirk A., Rahman, Md. Aejazur, Mackenzie, Jared S., Truebody, Barry E., Adamson, John H., Kunota, Tafara T. R., Bailey, Shannon M., Moellering, Douglas R., Lancaster, Jack R., Steyn, Adrie J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987094/
https://ncbi.nlm.nih.gov/pubmed/31992699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14132-y
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