Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

Hydrogen sulfide (H(2)S) is involved in numerous pathophysiological processes and shares overlapping functions with CO and •NO. However, the importance of host-derived H(2)S in microbial pathogenesis is unknown. Here we show that Mtb-infected mice deficient in the H(2)S-producing enzyme cystathionin...

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Publicado en:Nat Commun
Main Authors: Saini, Vikram, Chinta, Krishna C., Reddy, Vineel P., Glasgow, Joel N., Stein, Asaf, Lamprecht, Dirk A., Rahman, Md. Aejazur, Mackenzie, Jared S., Truebody, Barry E., Adamson, John H., Kunota, Tafara T. R., Bailey, Shannon M., Moellering, Douglas R., Lancaster, Jack R., Steyn, Adrie J. C.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987094/
https://ncbi.nlm.nih.gov/pubmed/31992699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14132-y
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