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Effect of Irbesartan-Poloxamer-188 Solid Dispersion on Intercellular Cell Adhesion Molecule-1 and Interleukin-8 on Hypertension Rats

BACKGROUND: Based on the Biopharmaceutics Classification System (BCS) system, irbesartan is a drug that belongs to the class II BCS group which has limitations in terms of dissolution rates with low bioavailability of 26% -60%. These limitations to bioavailability can be overcome by solid dispersion...

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Detalhes bibliográficos
Publicado no:Open Access Maced J Med Sci
Main Authors: Harmely, Fifi, Nasrul, Ellyza, Zaini, Erizal, Aldi, Yufri
Formato: Artigo
Idioma:Inglês
Publicado em: Republic of Macedonia 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986526/
https://ncbi.nlm.nih.gov/pubmed/32010369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3889/oamjms.2019.753
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