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Kneading Technique for Preparation of Binary Solid Dispersion of Meloxicam with Poloxamer 188

The aim of the present study was to enhance the dissolution rate of meloxicam (MLX), a practically water-insoluble drug by preparation of solid dispersion using a hydrophilic polymer, poloxamer 188 (PXM). The kneading technique was used to prepare solid dispersions. A 3(2) full factorial design appr...

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Detalhes bibliográficos
Main Authors: Ghareeb, Mowafaq M., Abdulrasool, Alaa A., Hussein, Ahmed A., Noordin, Mohammed I.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799582/
https://ncbi.nlm.nih.gov/pubmed/19862626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9316-0
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